Frank Schleck, wearing the overall leader’s yellow jersey, right, and his brother and teammate, Andy Schleck, wearing the best young rider’s white jersey, talk early in today’s stage of the Tour de France. Associated Press Photo.

JAUSIERS, France — Heading into the toughest stage of the Tour de France, Frank Schleck had a slim lead and Cadel Evans was in perfect position for the final weekend.

Schleck held on to the yellow jersey after the 16th stage Tuesday as the riders returned from Italy to France, where they faced a brutal day of climbing today that will conclude with the storied serpentine climb to L’Alpe d’Huez.

French rider Cyril Dessel won the 16th stage for his first stage victory in this race. He led a breakaway group of four to a downhill finish, completing the 98-mile trip from Cuneo, Italy, in 4 hours, 31 minutes, 27 seconds.

Schleck refrained from attacking during the mountain climbs, choosing to stay with his closest rivals. The Luxembourg rider finished 1 minute, 28 seconds behind Dessel and gained ground on two rivals — Russia’s Denis Menchov and Christian Vande Velde, an American contending in a major three-week race for the first time.

His main title rivals finished in the same time as Schleck. Bernhard Kohl of Austria remained second overall, 7 seconds behind, and pre-race favorite Evans of Australia was third, 8 seconds back. Carlos Sastre, a CSC teammate of Schleck, was fourth, 49 seconds behind.

Evans might have been the biggest winner Tuesday. He would be happy to stay 8 seconds behind Schleck through the mountains, then blow past his rival in the final time trial Saturday. The race ends Sunday in Paris.

“I’m very happy because it would have been too tough to do tomorrow’s stage with the yellow jersey,” said Roberto Damiani, sporting director for Evans’ Silence-Lotto team. “Evans is only 8 seconds behind, but the pressure is still on CSC right now.”

Menchov and Vande Velde had trouble on the concluding descent. Menchov simply couldn’t keep up with the other race leaders, while Vande Velde fell.

“Nothing special happened,” Menchov said. “I just lost the wheel. The upper sections of the downhill were very technical and difficult. ... I didn’t panic and I didn’t get scared, I just wanted to get down the mountain as safely and as fast as possible.”

Menchov lost 35 seconds and dropped from fourth to fifth overall, 1:13 behind. The damage for Vande Velde was far greater, with the Chicagoan losing 2:36 and dropping from fifth to sixth in the standings.

“I just hit a tight corner and fell,” said Vande Velde, who had already lost 35 seconds to the other leaders on the final climb up the Bonette-Restefond pass, a 16-mile uphill stretch.

Menchov and Vande Velde were not the only riders who had trouble going downhill.

South Africa’s John-Lee Augustyn was the first over the Bonette-Restefond peak, but he skidded off the road on a turn onto a rock-strewn mountainside. A spectator had to help up to the road before he rejoined the race.

There was to be even more climbing in Stage 17 today: a 131-mile ride featuring the fabled Galibier and Croix de Fer passes before the finish at L’Alpe d’Huez.

“With a stage like that looming, I think everyone had that thought in their minds today,” Damiani said.