Week 3 of Florida's grueling march through the Southeastern Conference takes the Gators to Auburn on Saturday. Florida replaced the Tigers as No. 2 in the AP Top 25 this week and is the only undefeated team left in the SEC.

Auburn is coming off its first loss of the season, and it was a doozy - 27-10 at home to unranked-at-the-time Arkansas. The Gators have won consecutive conference games at home against Alabama and LSU. They get a week off after this to prepare for Georgia on Oct. 28.

The picks:

Saturday

No. 1 Ohio State (minus 15) at Michigan State

Buckeyes have won four straight against Spartans ... OHIO STATE 37-17.

No. 2 Florida (plus 1) at No. 11 Auburn

Tigers have won five straight home games against top-10 teams ... AUBURN 23-20.

Arizona State (plus 19) at No. 3 Southern California

Trojans have won six straight in the series ... USC 30-17.

No. 4 Michigan (minus 61/2) at Penn State

WR Mario Manningham out for Wolverines ... MICHIGAN 17-13.

Syracuse (plus 25) at No. 5 West Virginia

Mountaineers have won four straight against Orange ... WEST VIRGINIA 38-17.

Baylor (plus 281/2) at No. 6 Texas

Unlikely battle for first in Big 12 South ... TEXAS 48-17.

Cincinnati (plus 27) at No. 7 Louisville

Louisville QB Brian Brohm might return from hand surgery ... LOUISVILLE 49-17.

No. 10 California (minus 71/2) at Washington State

Golden Bears have lost nine straight in Pullman dating back to 1979 ... WASHINGTON ST. 34-28.

Kentucky (plus 26) at No. 14 LSU

First meeting since LSU's Blue Grass Miracle, when Tigers won a 75-yard TD on final play ... LSU 41-14.

No. 15 Iowa (minus 171/2) at Indiana

Hawkeyes have won three straight and six of nine against Hoosiers ... IOWA 40-17.

Vanderbilt (plus 131/2) at No. 16 Georgia

Bulldogs have won 11 straight against Commodores, matching longest streak in series ... GEORGIA 29-13.

SE Missouri (no line) at No. 17 Arkansas

Razorbacks lead SEC in rushing ... ARKANSAS 45-14.

UCLA (plus 101/2) at No. 18 Oregon

Bruins have won four of five in Eugene ... OREGON 28-14.

No. 19 Missouri (minus 21/2) at Texas A&M

Tigers are last unbeaten team in Big 12 ... TEXAS A&M 24-20.

No. 21 Nebraska (minus 101/2) at Kansas State

Huskers lead Big 12 in rushing ... NEBRASKA 30-14.

Iowa State (plus 20) at No. 23 Oklahoma

Sooners TB Adrian Peterson vs. worst run defense in Big 12 ... OKLAHOMA 44-21.

No. 24 Rutgers (plus 11/2) at Navy

Middies lead nation in rushing and Scarlet Knights are 10th ... RUTGERS 27-24.

Minnesota (plus 81/2) at No. 25 Wisconsin

Battle for Paul Bunyan's Axe ... WISCONSIN 25-21.

Sunday

No. 20 Boise State (minus 26) at New Mexico State

Aggies lead nation in pass offense with coach Hal Mumme ... BOISE STATE 50-28.